Loading a large and growing cohort into Hail

Hi everyone,

I was wondering if there are any best practices for loading a large and growing cohort of samples into Hail? I stumbled upon this previous topic from Nov '16 with some good information:

Unfortunately, from what I can tell, adding samples incrementally is still challenging and would require continually merging vcf files as I receive new samples. Is this the case? While possible, this doesn’t seem like a nice solution since I’m working with a cohort of 100k+ samples.

Thank you for your time!

Would you mind reposting this to the user forum here? I think the wider community could definitely benefit from this discussion there. We also check that forum more frequently :slight_smile:

Sure! My bad, I didn’t realize there are multiple forums. Thanks!

For reference I reposted this question here: