I was wondering if there are any best practices for loading a large and growing cohort of samples into Hail? I stumbled upon this previous topic from Nov '16 with some good information:
Unfortunately, from what I can tell, adding samples incrementally is still challenging and would require continually merging vcf files as I receive new samples. Is this the case? While possible, this doesn’t seem like a nice solution since I’m working with a cohort of 100k+ samples.
Thank you for your time!